T cells engineered with chimeric antigen receptors (CARs) have emerged as a potent new class of therapeutics for cancer, based on their remarkable potency in blood cancers.Since the first clinical reports of their efficacy emerged 7 years ago, investigators have focused on the mechanisms and properties that make CARs Hutch effective or toxic, and t

Alessandro Bidossi,1 Marta Bottagisio,1 Roberta De Grandi,1 Lorenzo Drago,2 Elena De Vecchi11Laboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, Milan, Italy; 2Laboratory of Clinical Microbiology, Department of Biomedical Science for Health, University of Milan, Milan, ItalyPurpose: Persistence of skin and wound

Abstract Objective To assess variations in decisions to revascularise patients with coronary heart disease between general cardiologists, interventional cardiologists and cardiac surgeons Design Six cases of coronary heart disease were presented at an open meeting in a standard format including clinical details which might influence the decision to

An improved component modal Foot Care synthesis-based nonproportional mistuning method (ICMS-NPMM) is proposed to investigate mistuned turbine blisks (MTBs) since the high-fidelity finite element models (HFEMs) involve large number of computations, which leads to low calculation efficiency.To reduce degrees of freedom and suppress the flutter of MT

Most of control strategies 30" Cooktop are based on complex mathematical equations and the success of them is directly related to the precise acquisition of the mathematical model of the system.Virtual Model Control (VMC) allows the system to be mechanically controlled like a puppet with intuitive approaches instead of complex mathematical equation